Research involving human participants has been conducted in the Philippines since the beginning of the Spanish colonial period. Such studies are expected to adhere to internationally accepted ethical guidelines. This paper discusses trends in clinical research ethics in the Philippines during the American colonial period (1898‐1946). Specifically, studies were assessed on: 1) their observance of ethical protocols, including review; 2) identification of inclusion and exclusion criteria in the selection of participants; 3) use of vulnerable subjects; and 4) practice of the (...) informed consent process. Only the informed consent process had a significant logistic correlation with progression of years. Recruitment of vulnerable groups was common during this period; children and prisoners were the most common participants. Trends in medical ethics in the Philippines reflected those in the United States prior to the publication of the Nuremberg Code, which served as a milestone in the protection of human welfare in clinical research. (shrink)

We report on the deliberations of an interdisciplinary group of experts in science, law, and philosophy who convened to discuss novel ethical and policy challenges in stem cell research. In this report we discuss the ethical and policy implications of safety concerns in the transition from basic laboratory research to clinical applications of cell-based therapies derived from stem cells. Although many features of this transition from lab to clinic are common to other therapies, three aspects of stem cell biology pose (...) unique challenges. First, tension regarding the use of human embryos may complicate the scientific development of safe and effective cell lines. Second, because human stem cells were not developed in the laboratory until 1998, few safety questions relating to human applications have been addressed in animal research. Third, preclinical and clinical testing of biologic agents, particularly those as inherently complex as mammalian cells, present formidable challenges, such as the need to develop suitable standardized assays and the difficulty of selecting appropriate patient populations for early phase trials. We recommend that scientists, policy makers, and the public discuss these issues responsibly, and further, that a national advisory committee to oversee human trials of cell therapies be established. **NB we did not reccommend a NAC, we think it might be appropriate**. (shrink)

The subjective feeling of free choice is an important feature of human experience. Experimental tasks have typically studied free choice by contrasting free and instructed selection of response alternatives. These tasks have been criticised, and it remains unclear how they relate to the subjective feeling of freely choosing. We replicated previous findings of the fMRI correlates of free choice, defined objectively. We introduced a novel task in which participants could experience and report a graded sense of free choice. BOLD responses (...) for conditions subjectively experienced as free identified a postcentral area distinct from the areas typically considered to be involved in free action. Thus, the brain correlates of subjective feeling of free action were not directly related to any established brain correlates of objectively-defined free action. Our results call into question traditional assumptions about the relation between subjective experience of choosing and activity in the brain’s so-called voluntary motor areas. (shrink)

The essays pay particular attention to tensions associated with attempts to balance the economic with the non-economic objectives of higher education, and ...

If stem cell-based therapies are developed, we will likely confront a difficult problem of justice: for biological reasons alone, the new therapies might benefit only a limited range of patients. In fact, they might benefit primarily white Americans, thereby exacerbating long-standing differences in health and health care.

After witnessing extraordinary scientific and regulatory efforts to speed development of and access to new COVID-19 interventions, patients facing other serious diseases have begun to ask “where’s...

The Fundamentals of Care Framework is an evidence‐based, theory‐informed framework that conceptualises high‐quality fundamental care. The Framework places the nurse–patient relationship at the centre of care provision and outlines the nurse behaviours required for relationship development. Numerous instruments exist to measure behavioural aspects of the nurse–patient relationship; however, the literature offers little guidance on which instruments are psychometrically sound and best measure the core relationship elements of the Fundamentals of Care Framework. This study evaluated the quality of nurse–patient relationship instruments (...) by (1) assessing their content development and measurement properties (e.g. dimensionality, targeting, reliability, validity) and (2) mapping instrument content to the Framework's core relationship elements: trust, focus, anticipate, know, and evaluate. Twenty‐seven instruments were evaluated. Findings demonstrated that patients and nurses were rarely involved in item development. Most instruments exhibited poor measurement properties, with only one instrument having complete information on all quality indicators. Instrument content focused primarily on nurses getting to know patients and earning their trust, with only 54, 18, and 1 item(s), respectively, measuring ‘focus’, ‘anticipate’ and ‘evaluate’. Hence, there does not appear to be a robust instrument measuring behavioural aspects of nurse–patient relationships, nor one capturing the relationship elements of the Fundamentals of Care Framework. (shrink)

Cet ouvrage fait partie de la collection « Louise Michel : Œuvres » lancée par le laboratoire LIRE et par Xavière Gauthier dès 1999 afin de rendre son œuvre accessible et d’en montrer la complexité et l’intérêt littéraire. C’est la première édition critique de trois romans, Les microbes humains (p. 47-207), Le monde nouveau (p. 211-384) et Le claque-dents (p. 387-562) qui datent respectivement de 1886, 1888 et 1890 (p. 11). Pour le troisième tome uniquement, un tableau des correspondances (...) ent... (shrink)

We examine how prior mental health predicts hopes and how hopes predict subsequent mental health, testing hypotheses in a longitudinal study with an Australian nation-wide adult sample regarding mental health consequences of the COVID-19 outbreak during its initial stage. Quota sampling was used to select a sample representative of the adult Australian population in terms of age groups, gender, and geographical location. Mental health measures were selected to include those with the best psychometric properties. Hypotheses were tested using generalized linear (...) models with random intercepts, with the type of GLM determined by the nature of the dependent variable. Greater anxiety, depression, distress, and loneliness predict less hope, but impaired quality of life and stress positively predict hopes of gaining new skills. Distress and loneliness predict hopes for social connectedness and an improved society, suggesting that predictors of hope depend on what is hoped for. These findings suggest the need for more nuanced theories of hope. Greater hopes for societal improvement predict lower anxiety, depression, distress, and impaired quality of life, but greater hopes for skills and better mental health predict higher levels of these covariates. Moreover, when relevant prior psychological states are more intense, the impact of hope state declines. These findings indicate that the consequences of hope are heterogeneous, and suggest a possible explanation for the seemingly inconsistent therapeutic effectiveness of raising hope. (shrink)

Cartesian Views is a fitting tribute to a man of many parts, to use Alison Wylie’s apt description . Richard A. Watson has provoked, evoked, and invoked new directions in Cartesian scholarship—both methodologically and substantively. Watson’s Downfall of Cartesianism and its sequel, The Breakdown of Metaphysics , have become required reading for students of early modern philosophy and are largely responsible for the revival of many “minor” Cartesians, while serving as sourcebook for methodological attention to history and rational reconstruction. (...) Cartesian Views is an important collection that hearkens a forty-year retrospective of Cartesian studies while simultaneously turning our sights to what lies in the future.Although an eclectic collection, each paper in the volume reflects some counterpoint to, advancement of, or commentary upon some aspect, claim, argument, or theme found in Watson’s philosophical works. The opening paper by Nadler questions Watson’s view that dualism and the problem of mind-body interaction was the central issue that stimulated. (shrink)

The most popular uniting theme in feminist peace literature grounds women's peace work in mothering. I argue if maternal arguments do not address the variety of relationships different races and classes of mothers have to institutional violence and/or the military, then the resulting peace politics can only draw incomplete conclusions about the relationships between maternal work/thinking and peace. To illustrate this I compare two models of mothering: Sara Ruddick's decription of "maternal practice" and Patricia Hill Collins's account of racial-ethnic (...) women's "motherwork.". (shrink)

This essay investigates the marginalisation in eighteenth-century literary theoretical discussions of a category of emotion, ‘the affections’, which plays a significant role elsewhere in eighteenth-century thought, especially in moral philosophy and theology. It proposes that affections are incompatible with a series of principles that underpin dominant concepts of the literary in early and mid-eighteenth-century literary criticism by authors including Kames, Burke, Alison, Duff, Brown, Du Bos, Trapp and Beattie, many of whom were associated with the Scottish Enlightenment. By analysing (...) eighteenth-century theories of the perceived obscurity of literary emotions in comparison with the emotions of the other fine arts , and by highlighting the perceived distinction of literary emotions from what theorists of the period term ‘reality’, it shows how the supremacy of the belief that literary merit is tied to the individuality, particularity, and plausibility of represented emotion gives rise to a prioritisation of passions over affections in literary critical discussions about the emotions. (shrink)

The most popular uniting theme in feminist peace literature grounds women's peace work in mothering. I argue if maternal arguments do not address the variety of relationships different races and classes of mothers have to institutional violence and/or the military, then the resulting peace politics can only draw incomplete conclusions about the relationships between maternal work/thinking and peace. To illustrate this I compare two models of mothering: Sara Ruddick's decription of "maternal practice" and Patricia Hill Collins's account of racial-ethnic (...) women's "motherwork.". (shrink)

Imagining Dewey' features productive (re)interpretations of 21st century experience using the lens of John Dewey's 'Art as Experience', through the doubled task of putting an array of international philosophers, educators, and artists-researchers in transactional dialogue and on equal footing in an academic text. This book is a pragmatic attempt to encourage application of aesthetic learning and living, ekphrasic interpretation, critical art and agonist pluralism.0There are two foci: (a) Deweyan philosophy and educational themes with (b) analysis and examples of how educators, (...) artists, and researchers envision and enact artful meaning making. This structure meets the needs of university and high school audiences, who are accustomed to learning about challenging ideas through multimedia and aesthetic experience.00Contributors are: James M. Albrecht, Adam I. Attwood, John Baldacchino, Carolyn L. Berenato, M. Cristina Di Gregori, Holly Fairbank, Jim Garrison, Amanda Gulla, Bethany Henning, Jessica Heybach, David L. Hildebrand, Ellyn Lyle, Livio Mattarollo, Christy McConnell Moroye, Maria-Isabel Moreno-Montoro, Maria Martinez Morales, Stephen M. Noonan, Louise G. Phillips, Scott L. Pratt, Joaquin Roldan, Leopoldo Rueda, Tadd Ruetenik, Leisa Sasso, Bruce Uhrmacher, David Vessey, Ricardo Marin Viadel, Sean Wiebe, Li Xu and Martha Patricia Espiritu Zavalza. (shrink)

In this compelling volume, ten distinguished thinkers -- William G. Lycan, Galen Strawson, Jeffrey Poland, Georges Rey, Frances Egan, Paul Horwich, Peter Ludlow, Paul Pietroski, Alison Gopnik, and Ruth Millikan -- address a variety of conceptual issues raised in Noam Chomsky's work. Distinguished list of critics: William G. Lycan, Galen Strawson, Jeffrey Poland, Georges Rey, Frances Egan, Paul Horwich, Peter Ludlow, Paul Pietroski, Alison Gopnik, and Ruth Millikan. Includes Chomsky's substantial new replies and responses to each essay. The (...) best critical introduction to Chomsky's thought as a whole. (shrink)

Cartesian Views is a fitting tribute to a man of many parts, to use Alison Wylie’s apt description . Richard A. Watson has provoked, evoked, and invoked new directions in Cartesian scholarship—both methodologically and substantively. Watson’s Downfall of Cartesianism and its sequel, The Breakdown of Metaphysics , have become required reading for students of early modern philosophy and are largely responsible for the revival of many “minor” Cartesians, while serving as sourcebook for methodological attention to history and rational reconstruction. (...) Cartesian Views is an important collection that hearkens a forty-year retrospective of Cartesian studies while simultaneously turning our sights to what lies in the future.Although an eclectic collection, each paper in the volume reflects some counterpoint to, advancement of, or commentary upon some aspect, claim, argument, or theme found in Watson’s philosophical works. The opening paper by Nadler questions Watson’s view that dualism and the problem of mind-body interaction was the central issue that stimulated. (shrink)

Descartes’ mind-body dualism and his quest for objective knowledge can appear de-humanizing. My aim in this paper is to re-humanize Descartes. When we take a closer look at what Descartes actually says about human beings, it casts his entire thought in a much different light.

This essay explores how the social location of white traitorous identities might be understood. I begin by examining some of the problematic implications of Sandra Harding's standpoint framework description of race traitors as 'becoming marginal.' I argue that the location of white traitors might be better understood in terms of their 'decentering the center.' I distinguish between 'privilege-cognizant' and 'privilege-evasive' white scripts. Drawing on the work of Marilyn Frye and Anne Braden, I offer an account of the contrasting perceptions and (...) behaviors of white who animate one type of script and those who struggle to forge the other type. I use Maria Lugones account of identity and notions of 'world travel' and 'loving perception' and Aristotle's virtue theory to explicate the ways whites, and white feminists in particular, might cultivate a traitorous character conducive to an antiracist politics. (shrink)

I have tried to motivate the claim that the interlude has been somewhat over-read as a “physics” and under-read as a guide to understanding Spinoza’s picture of the relationship between the mind and the body – in particular, of Spinoza’s account of how the mind represents bodies through sense perception. It does not inform us about the nature of extension or motion, and its use of those terms offers little illumination. The real argumentative and conceptual work of the interlude is (...) attribute-neutral. (shrink)

A dialogue between virtue and care ethics is formed as a step towards meeting Pellegrino's challenge to create a more comprehensive moral philosophy. It is also a dialogue between nursing and medicine since each practice draws on the Greek Virtue Tradition and the Judeo-Christian Tradition of care differently. In the Greek Virtue Tradition, the point of scrutiny lies in the inner character of the actor, whereas in the Judeo-Christian Tradition the focus is relational, i.e. how virtues are lived out in (...) specific relationships, particularly unequal relationships where vulnerability of one of the members is an issue. In a care ethic relational qualities such as attunement rather than inner qualities are the point of scrutiny. A dialogue between these two traditions makes it possible to consider the relational virtues and skills of openness and responsiveness that are required for a respectful meeting of the other. (shrink)

The article asks whether political anger has a legitimate place in a democracy, as this is a political system designed to resolve conflicts by peaceful negotiation. It distinguishes personal from social anger and political anger, to focus explicitly on the latter. It argues that both the feeling and expression of political anger are subject to normative constraints, often specific to social status and gender. The article examines arguments, including those of Seneca, in favour of an anger-free society. It concludes, however, (...) that a democracy cannot dispense with political anger, which has a vital role to play in protecting things of value. This role demands a civic education such that when democratic values are under threat citizens will not feel apathetic or simply fearful, but angry and possessed of a repertoire of ways of expressing democratic anger. (shrink)

This article analyzes feminist organizations as a species of social movement organization. It identifies 10 dimensions for comparing feminist and nonfeminist organizations or for deriving types of feminist organizations and analyzing them. The dimensions are feminist ideology, feminist values, feminist goals, feminist outcomes, founding circumstances, structure, practice, members and membership, scope and scale, and external relations. I argue that many scholars judge feminist organizations against an ideal type that is largely unattainable and that excessive attention has been paid to the (...) issue of bureaucracy versus collectivism to the neglect of other organizational qualities. The varieties of ideology, form, and strategy that feminist organizations embody should be analyzed in relation to outcomes for women, the women's movement, and society. As has recently begun to occur, feminist scholars are encouraged to claim the topic of feminist organizations for themselves. (shrink)

I agree with Dyck’s basic claim that Kant follows the methodology of Rational Psychology in setting up his critique of it: He starts as it starts, with an existential proposition ‘I think.’ On the other hand, I am not convinced of Dyck’s use of the Dreams essay in establishing a timeline for the development of Kant’s views on inner sense. That essay is evidence that Kant thinks that Schwendenborg’s metaphysics is ungrounded, because he has a crazy sort of inner sense, (...) but it does not show that Kant rejected a more standard internal sense at this time. I also suggest that some of Kant’s vacillation about inner sense depends on an unusual feature of his doctrine of the representations of space and time: They are composed of both sensory and a priori elements. My hypothesis is that the seeming vacillation about inner sense may be a reflection of whether whether he is considering it broadly, as a faculty that provides intuitions with a particular form, or whether he is restricting what it provides to what can be sensed. (shrink)

A recent special issue in the Journal of Business Ethics gathered together a variety of papers addressing the challenges of putting virtue ethics into practice :563–565, 2013). The editors prefaced their outline of the various papers with the assertion that exploring the practical dimension of virtue ethics can help business leaders discover their proper place in working for a better world, as individuals and within the family, the business community and society in general :563–565, 2013). Scholars are yet to explore (...) the role of virtuous organisational leaders in the pursuit of Eudaimonia. This paper is a qualitative study which considered company directors’ self-understandings in light of a virtue ethics conceptual framework. The aim of the study is to explore whether virtue ethics rather than deontology and consequentialism is a better vehicle for expressing directors’ self-understandings about their ideals and role. (shrink)

Doctors routinely refuse donation offers from prospective living kidney donors with certain comorbidities such as diabetes or obesity out of concern for donor wellbeing. This refusal occurs despite the ongoing shortage of kidney transplants and the superior performance of living donor kidney transplants compared to those from deceased donors. In this paper, we argue that this paternalistic refusal by doctors is unjustified and that, within limits, there should be greater acceptance of such donations. We begin by describing possible weak and (...) strong paternalistic justifications of current conservative donor acceptance guidelines and practices. We then justify our position by outlining the frequently under-recognised benefits and the routinely overestimated harms of such donation, before discussing the need to respect the autonomy of willing donors with certain comorbidities. Finally, we respond to a number of possible objections to our proposal for more liberal kidney donor acceptance criteria. We use the situation in Australia as our case study, but our argument is applicable to comparable situations around the world. (shrink)